mechanism of action

Aluminum Acetate is an astringent. An astrignent is a chemical that tends to shrink or constrict body tissues, usually locally after topical medicinal application. The shrinkage or constriction is through osmotic flow of water (or other fluids) away from the area where the astringent was applied. Astringent medicines cause shrinkage of mucous membranes or exposed tissues and are often used internally to check discharge of blood serum or mucous secretions. This can happen with a sore throat, hemorrhages, diarrhea, or with peptic ulcers. Externally applied astringents, which cause mild coagulation of skin proteins, dry, harden, and protect the skin. Acne sufferers are often advised to use astringents if they have oily skin. Astringents also help heal stretch marks and other scars. Mild astringent solutions are used in the relief of such minor skin irritations as those resulting from superficial cuts, allergies, insect bites, or fungal infections such as athlete's foot.

drug interactions

Amprenavir: The antiacid decreases the absorption of amprenavir

Atazanavir: This gastric pH modifier decreases the levels/effects of atazanavir

Chloroquine: The antiacid decreases the absorption of chloroquine

Ciprofloxacin: Formation of non-absorbable complexes

Clindamycin: The aluminium salt decreases the absorption of lincosamides

Clodronate: Formation of non-absorbable complexes

Dapsone: Formation of non-absorbable complexes

Deferasirox: Possible physicochemical interaction

Delavirdine: The antiacid decreases the effect of delavirdine

Demeclocycline: Formation of non-absorbable complexes

Doxycycline: Formation of non-absorbable complexes

Etidronic acid: Formation of non-absorbable complexes

Fosamprenavir: The antiacid decreases the absorption of amprenavir

Gatifloxacin: Formation of non-absorbable complexes

Gemifloxacin: Formation of non-absorbable complexes

Grepafloxacin: Formation of non-absorbable complexes

Ibandronate: Formation of non absorbable complexes

Indinavir: The antacid decreases the absorption of indinavir

Itraconazole: Aluminum-containing antacids may decrease the effect of itraconazole.

Ketoconazole: Aluminum-containing antacids may decrease the effect of ketoconazole.

Levofloxacin: Formation of non-absorbable complexes

Lincomycin: The aluminium salt decreases the absorption of lincosamides

Minocycline: Formation of non-absorbable complexes

Moxifloxacin: Formation of non-absorbable complexes

Norfloxacin: Formation of non-absorbable complexes

Ofloxacin: Formation of non-absorbable complexes

Penciclovir: The multivalent agent decreases the effect of penicillamine

Polystyrene sulfonate: Risk of alkalosis in renal impairment

Tetracycline: Formation of non-absorbable complexes

Trovafloxacin: Aluminum may decrease the absorption of orally administered Trovafloxacin. Administer Trovafloxacin 2 hours before or 6 hours after a dose of the aluminum containing agent to minimize the interaction.