Company InfoNewsInvestor InformationResearchDevelopmentCareersBusiness DevelopmentResourcesDrugs databaseBack to the home pageSearch  
Drugs database
Drugs A-Z

Brands A-Z

Drugs by categories

Drugs by manufacturer

Drugs by packager

Antibiotics for sale

Online Viagra bestellen in Nederland

Home / Drugs / Starting with A / Arcitumomab 		 
Arcitumomab
  

Reduced Fab fragment of the murine IgG1 monoclonal antibody IMMU-4 (also called NP-4) with specificity for carcinoembryonic antigen (CEA) covalently labeled with Technitium 99. The molecule has a molecular weight of ~54,000 Daltons.
BrandsCEA-Scan
CategoriesDiagnostic Agents
Imaging Agents
PackagersI
h
Synonymsanti-Carcinoembryonic Antigen Monoclonal Antibody Fab' Fragment
IMMU-4

indication

For imaging colorectal tumors

pharmacology

Binds to the carcinoembryonic antigen, which is a cell surface protein generally overexpressed in colon (and other) cancers. The radioactive Tc99, which is covalently attached to the antibody, allows radiodiagnostic detection of CEA expressing cells and tumors

mechanism of action

Binds selectively to cell-surface carcinoembryonic antigen (CEA) expressed on colorectal tumors.

biotransformation

Most likely removed by opsonization via the reticuloendothelial system, or by human antimurine antibody production

half life

Approximately 1 hour

Terms of Use