Home / Drugs / Starting with A /
indicationWhen used in medicine, it physically binds to acids and toxic substances in the stomach and digestive tract. For that reason, it has often been used in antidiarrheal medications. Attapulgite is an adsorbent.
pharmacologyAttapulgite is an adsorptive magnesium aluminium phyllosilicate which binds to toxins, bacteria and water.
mechanism of actionAttapulgite adsorbs water, toxins and bacteria, contributing to firmer stools, reducing fluid loss from diarrhea.
drug interactionsChloroquine: The antiacid decreases the absorption of chloroquine
Clindamycin: The aluminium salt decreases the absorption of lincosamides
Demeclocycline: Formation of non-absorbable complexes
Doxycycline: Formation of non-absorbable complexes
Lincomycin: The aluminium salt decreases the absorption of lincosamides
Minocycline: Formation of non-absorbable complexes
Penciclovir: The multivalent agent decreases the effect of penicillamine
Tetracycline: Formation of non-absorbable complexes