indication

Used to prevent and treat nausea and vomiting associated with anesthesia and surgery, administered intramuscularly or intravenously.

pharmacology

Benzquinamide is an antiemetic compound with antihistaminic, mild anticholinergic, and sedative properties.

mechanism of action

The mechanism of action is not known, but presumably benzquinamide works via antagonism of muscarinic acetycholine receptors and histamine H1 receptors.

absorption

Incomplete, with 33–39% bioavailability via the capsule and suppository routes, relative to the intramuscular route.

half life

1-1.6 hours (for all formulations)