Company InfoNewsInvestor InformationResearchDevelopmentCareersBusiness DevelopmentResourcesDrugs databaseBack to the home pageSearch  
Drugs database
Drugs A-Z

Brands A-Z

Drugs by categories

Drugs by manufacturer

Drugs by packager

Antibiotics for sale

Online Viagra bestellen in Nederland

Home / Drugs / Starting with C / Cefaclor

Semisynthetic, broad-spectrum antibiotic derivative of cephalexin. [PubChem]
Ceclor CD
CategoriesAnti-Bacterial Agents
ManufacturersEli lilly and co
Ceph international corp
Clonmel healthcare ltd
Hikma pharmaceuticals
Ivax pharmaceuticals inc sub teva pharmaceuticals usa
Marsam pharmaceuticals llc
Ranbaxy pharmaceuticals inc
Teva pharmaceuticals usa inc
Yung shin pharmaceutical industrial co ltd
Acs dobfar info sa
Ranbaxy laboratories ltd
World gen llc
PackagersAdvanced Pharmaceutical Services Inc.
Aidarex Pharmacuticals LLC
Alvogen Inc.
A-S Medication Solutions LLC
Bryant Ranch Prepack
C.O. Truxton Inc.
Carlsbad Technology Inc.
Corepharma LLC
DAVA Pharmaceuticals
Direct Dispensing Inc.
Dispensing Solutions
Diversified Healthcare Services Inc.
Eli Lilly & Co.
H.J. Harkins Co. Inc.
Ivax Pharmaceuticals
Jazeera Pharmaceutical Industries
Lake Erie Medical and Surgical Supply
Lilly Del Caribe Inc.
Major Pharmaceuticals
Novopharm Ltd.
Nucare Pharmaceuticals Inc.
Palmetto Pharmaceuticals Inc.
Par Pharmaceuticals
Patheon Inc.
PD-Rx Pharmaceuticals Inc.
Pharma Pac LLC
Pharmaceutical Utilization Management Program VA Inc.
Physicians Total Care Inc.
Preferred Pharmaceuticals Inc.
Ranbaxy Laboratories
Rebel Distributors Corp.
Redpharm Drug
Southwood Pharmaceuticals
Teva Pharmaceutical Industries Ltd.
West-Ward Pharmaceuticals
World Gen LLC
Yung Shin Pharmaceutical Industry Ltd.
Cefaclor anhydrous
Cefaclorum [INN-Latin]


For the treatment of certain infections caused by bacteria such as pneumonia and ear, lung, skin, throat, and urinary tract infections.


Cefaclor is a second generation cephalosporin antibiotic with a spectrum resembling first-generation cephalosporins. In vitro tests demonstrate that the bactericidal action of the cephalosporins results from inhibition of cell-wall synthesis. Cefaclor has been shown to be active against most strains of the following microorganisms, both in vitro and in clinical infections: Gram positive aerobes - Staphylococci (including coagulase-positive, coagulase-negative, and penicillinase-producing strains), Streptococcus pneumoniae, and Streptococcus pyogenes (group A ß-hemolytic streptococci). Gram-negative aerobes - Escherichia coli, Haemophilus influenzae (including ß-lactamase-producing ampicillin-resistant strains), Klebsiella sp, and Proteus mirabilis.

mechanism of action

Cefaclor, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins. It is possible that cefaclor interferes with an autolysin inhibitor.


Symptoms of overdose include diarrhea, nausea, stomach upset, and vomiting.


No appreciable biotransformation in liver (approximately 60% to 85% of the drug is excreted unchanged in the urine within 8 hours).


Well absorbed after oral administration, independent of food intake.

half life

0.6-0.9 hour

route of elimination

Approximately 60% to 85% of the drug is excreted unchanged in the urine within 8 hours, the greater portion being excreted within the first 2 hours.