Company InfoNewsInvestor InformationResearchDevelopmentCareersBusiness DevelopmentResourcesDrugs databaseBack to the home pageSearch  
Drugs database
Drugs A-Z

Brands A-Z

Drugs by categories

Drugs by manufacturer

Drugs by packager

Antibiotics for sale

Online Viagra bestellen in Nederland

Home / Drugs / Starting with C / Cetirizine

A potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects. [PubChem]
Hitrizin Film Tablet
Zyrtec Syrup
CategoriesAnti-Allergic Agents
Histamine H1 Antagonists, Non-Sedating
ManufacturersBanner pharmacaps inc
Actavis mid atlantic llc
Amneal pharmaceuticals
Apotex inc
Aurobindo pharma ltd
Cypress pharmaceutical inc
Dr reddys laboratories ltd
Perrigo israel pharmaceuticals ltd
Ranbaxy laboratories ltd
Sun pharmaceutical industries inc
Taro pharmaceutical industries ltd
Teva pharmaceuticals usa
Vintage pharmaceuticals llc
Wockhardt ltd
Perrigo r and d co
Mcneil consumer healthcare div mcneil ppc inc
Caraco pharmaceutical laboratories ltd
Sandoz inc
Pfizer inc
Actavis elizabeth llc
Amneal pharmaceuticals ny llc
Cadista pharmaceuticals inc
Contract pharmacal corp
Mylan pharmaceuticals inc
Orchid healthcare
Torrent pharmaceuticals llc
Unichem laboratories ltd
Unique pharmaceutical laboratories
PackagersActavis Group
Advanced Pharmaceutical Services Inc.
Apotex Inc.
Apotheca Inc.
AQ Pharmaceuticals Inc.
Atlantic Biologicals Corporation
Aurobindo Pharma Ltd.
Bryant Ranch Prepack
Caraco Pharmaceutical Labs
Cardinal Health
CVS Pharmacy
Cypress Pharmaceutical Inc.
Direct Dispensing Inc.
Direct Pharmaceuticals Inc.
Dispensing Solutions
Diversified Healthcare Services Inc.
Doctor Reddys Laboratories Ltd.
EZ-EM Inc.
H.J. Harkins Co. Inc.
J.B. Chemicals & Pharmaceuticals
Kaiser Foundation Hospital
L Perrigo Co.
Lake Erie Medical and Surgical Supply
McNeil Laboratories
Medvantx Inc.
Murfreesboro Pharmaceutical Nursing Supply
Nucare Pharmaceuticals Inc.
Ohm Laboratories Inc.
PD-Rx Pharmaceuticals Inc.
Perrigo Co.
Pfizer Inc.
Pharmacy Service Center
Physicians Total Care Inc.
Prepackage Specialists
Prepak Systems Inc.
Ranbaxy Laboratories
Redpharm Drug
Resource Optimization and Innovation LLC
Southwood Pharmaceuticals
Teva Pharmaceutical Industries Ltd.
US Pharmaceutical Group
Vangard Labs Inc.
Warner Chilcott Co. Inc.
Wockhardt Ltd.
SynonymsCetirizina [Spanish]
Cetirizinum [Latin]
Cetrizine Hcl


For the relief of symptoms associated with seasonal allergic rhinitis, perennial allergic rhinitis and the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria


Cetirizine, the active metabolite of the piperazine H1-receptor antagonist hydroxyzine, is used to treat chronic idiopathic urticaria, perennial allergic rhinitis, seasonal allergic rhinitis, allergic asthma, physical urticaria, and atopic dermatitis.

mechanism of action

Cetirizine competes with histamine for binding at H1-receptor sites on the effector cell surface, resulting in suppression of histaminic edema, flare, and pruritus. The low incidence of sedation can be attributed to reduced penetration of cetirizine into the CNS as a result of the less lipophilic carboxyl group on the ethylamine side chain.


Somnolence (sleepiness or unusual drowsiness), restlessness, irritability


mean peak plasma concentration (Cmax) of 114 ng/mL at a time (Tmax) of 2.2 hours postdose was observed for cetirizine

half life

8.3 hours