Company InfoNewsInvestor InformationResearchDevelopmentCareersBusiness DevelopmentResourcesDrugs databaseBack to the home pageSearch  
Drugs database
Drugs A-Z

Brands A-Z

Drugs by categories

Drugs by manufacturer

Drugs by packager

Antibiotics for sale

Online Viagra bestellen in Nederland

Home / Drugs / Starting with C / Choriogonadotropin alfa
Choriogonadotropin alfa

Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). The primary structure of the alpha-chain of r-hCG is identical to that of the alpha-chain of hCG, FSH and LH.
CategoriesFertility Agents
ManufacturersEmd serono inc
Ferring pharmaceuticals inc
App pharmaceuticals llc
Bel mar laboratories inc
Bristol myers squibb
Organon usa inc
PackagersEMD Canada Inc.
Ferring Pharmaceuticals Inc.
Merck KGaA
Organon Pharmaceuticals
Choriogonadotropin beta chain precursor
Chorionic gonadotrophin beta subunit


For the treatment of female infertility


Choriogonadotropin alfa is used to treat female infertility, Choriogonadotropin alfa stimulates late follicular maturation and resumption of oocyte meiosis, and initiates rupture of the pre-ovulatory ovarian follicle. Ovidrel is an analogue of Luteinizing Hormone (LH) and binds to the LH/hCG receptor of the granulosa and theca cells of the ovary to effect these changes in the absence of an endogenous LH surge.

mechanism of action

Choriogonadotropin alfa binds to the Follicle stimulating hormone receptor which results in ovulation in the absence of sufficient endogenous Luteinizing hormone.


The mean absolute bioavailability following a single subcutaneous injection to healthy female volunteers is about 40%.

half life

The mean terminal half-life is about 29 ± 6 hours (initial half-life is 4.5 ± 0.5 hours).

route of elimination

One-tenth of the dose is excreted in the urine.