indication

Fenoterol is used for the treatment of asthma.

pharmacology

Fenoterol is a beta agonist designed to open up the airways to the lungs by decreasing bronchconstriction.

mechanism of action

Beta(2)-receptor stimulation in the lung causes relaxation of bronchial smooth muscle, bronchodilation, and increased bronchial airflow.

toxicity

Symptoms of overdose include angina (chest pain), dizziness, dry mouth, fatigue, flu-like symptoms, headache, heart irregularities, high or low blood pressure, high blood sugar, insomnia, muscle cramps, nausea, nervousness, rapid heartbeat, seizures, and tremor.

biotransformation

Hepatic.

drug interactions

Acebutolol: Antagonism

Alseroxylon: Increased arterial pressure

Amitriptyline: The tricyclic antidepressant, amitriptyline, may increase the sympathomimetic effect of fenoterol.

Amoxapine: The tricyclic antidepressant, amoxapine, increases the sympathomimetic effect of fenoterol.

Atenolol: Antagonism

Betaxolol: Beta-Blockers (Beta-1 Selective) like betaxolol may diminish the bronchodilatory effect of Beta2-Agonists like fenoterol. Therapy should be monitored.

Bevantolol: Antagonism

Bisoprolol: Antagonism

Carteolol: Antagonism

Carvedilol: Antagonism

Clomipramine: The tricyclic antidepressant, clomipramine, increases the sympathomimetic effect of fenoterol.

Deserpidine: Increased arterial pressure

Desipramine: The tricyclic antidepressant, desipramine, increases the sympathomimetic effect of fenoterol.

Doxepin: The tricyclic antidepressant, doxepin, increases the sympathomimetic effect of fenoterol.

Esmolol: Antagonism

Imipramine: The tricyclic antidepressant, imipramine, increases the sympathomimetic effect of fenoterol.

Isocarboxazid: Increased arterial pressure

Labetalol: Antagonism

Linezolid: Possible increase of arterial pressure

Methyldopa: Increased arterial pressure

Metoprolol: Antagonism

Midodrine: Increased arterial pressure

Moclobemide: Moclobemide increases the sympathomimetic effect of fenoterol.

Nadolol: Antagonism

Nortriptyline: The tricyclic antidepressant, nortriptyline, increases the sympathomimetic effect of fenoterol.

Oxprenolol: Antagonism

Pargyline: Increased arterial pressure

Penbutolol: Antagonism

Phenelzine: Increased arterial pressure

Pindolol: Antagonism

Practolol: Antagonism

Propranolol: Antagonism

Protriptyline: The tricyclic antidepressant, protriptyline, increases the sympathomimetic effect of fenoterol.

Rasagiline: Increased arterial pressure

Reserpine: Increased arterial pressure

Sotalol: Antagonism

Timolol: Antagonism

Tranylcypromine: Increased arterial pressure

Trimipramine: The tricyclic antidepressant, trimipramine, increases the sympathomimetic effect of fenoterol.