indication

For diagnostic use only. Indicated for adults and children, age 2 and over, for contrast enhancement during cranial and spinal MRI and for contrast-enhanced magnetic resonance angiography (CE-MRA). Gadobutrol is particularly suited for where the exclusion or demonstration of additional pathology may influence the choice of therapy or patient management, for detection of very small lesions and for visualization of tumors that do not readily take up contrast media. May also be suitable for perfusion studies for the diagnosis of stroke, detection of focal cerebral ischemia and tumor perfusion.

drug interactions

Artemether: Additive QTc-prolongation may occur. Concomitant therapy should be avoided.

Lumefantrine: Additive QTc-prolongation may occur. Consider alternate therapy or monitor closely for QTc-prolongation.