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Home / Drugs / Starting with L / Lisuride 		 
Lisuride
  

An ergot derivative that acts as an agonist at dopamine D2 receptors (dopamine agonists). It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (serotonin agonists). [PubChem]
BrandsLisurida [INN-Spanish]
Lisuride [INN]
Lisuride Maleate
Lisuridum [INN-Latin]
Lysuride
CategoriesAntiparkinson Agents
Antidyskinetics
Dopamine Agonists
Serotonin Agonists

indication

For the management of Parkinson's Disease

mechanism of action

Lisuride is an anti-Parkinson drug chemically related to the dopaminergic ergoline Parkinson's drugs. Lisuride binds to the 5-HT(1A) and 5-HT(2A/2C) receptors. It is also thought to bind to the dopamine receptor and to act as a dopamine agonist. Evidence has also emerged that Lisuride also binds to the Histamine H1 receptor. Lisuride is also used to lower prolactin and, in low doses, to prevent migraine attacks.

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