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Home / Drugs / Starting with P / Pemoline


For treatment of Attention Deficit Hyperactivity Disorder (ADHD)


Pemoline belongs to the group of medicines called central nervous system (CNS) stimulants. It is used to treat attention deficit hyperactivity disorder (ADHD). Pemoline stimulates the brain, probably by affecting neurotransmitters, the chemicals in the brain that nerves use to communicate with each other.


Side effects include insomnia, anorexia, stomach ache, skin rashes, increased irritability, mild depression, nausea, dizziness, headache, drowsiness, and hallucinations




Pemoline is rapidly absorbed from the gastrointestinal tract

half life

The serum half-life of pemoline is approximately 12 hours.

route of elimination

Pemoline is excreted primarily by the kidneys with approximately 50% excreted unchanged and only minor fractions present as metabolites.