|A broad-spectrum antimicrobial isolated from Streptomyces ribosifidicus. [PubChem]
Antibiotic SF 733
mechanism of action
Aminoglycosides work by binding to the bacterial 30S ribosomal subunit (some work by binding to the 50S subunit), inhibiting the translocation of the peptidyl-tRNA from the A-site to the P-site and also causing misreading of mRNA, leaving the bacterium unable to synthesize proteins vital to its growth. However, their exact mechanism of action is not fully known.