Rolicyclidine (PCPy) is a dissociative anesthetic drug with hallucinogenic and sedative effects. Due to its similarity in effects to PCP, PCPy was placed into the Schedule I list of illegal drugs in the 1970s, although it has never been widely abused and is now little known. |
Categories | Hallucinogens
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Synonyms | 1-(1-phenylcyclohexyl)pyrrolidine DEA No. 7458 PCPy Pyrrolidine analog of phencyclidine Roliciclidina [INN-Spanish] Rolicyclidinum [INN-Latin]
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indication
Rolicyclidine has anesthetic properties and can induce a sedative effect.
pharmacology
Rolicyclidine is similar in effects to phencyclidine but is slightly less potent and has less stimulant effects. Instead it acts by inducing a sedative effect described as being somewhat similar to a barbiturate, but with additional PCP-like dissociative, anaesthetic and hallucinogenic effects.
mechanism of action
Rolicyclidine works primarily as an NMDA receptor antagonist, which blocks the activity of the NMDA Receptor.