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Home / Drugs / Starting with S / Streptolydigin
 
Streptolydigin
 

CategoriesAntibacterial Agents
SynonymsAntibiotic D-45
Portamycin

pharmacology

Streptolydigin is an antibiotic which works by blocking nucleic acid chain elongation by binding to the polymerase, thus stopping RNA polymerase activity inside a cell. Specifically, it inhibits the assembly of the RNA polymerase II transcription complex and DNA polymerase III transcription. It is active against a number of gram positive bacteria.

 

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