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Home / Drugs / Starting with S / Succinic acid
Succinic acid

A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
Kyselina jantarova
CategoriesAnti-Ulcer Agents
Dietary supplement
Radiation-Protective Agents
PackagersBreckenridge Pharmaceuticals
Contract Pharm
J T Baker
KV Pharmaceutical Co.
Murfreesboro Pharmaceutical Nursing Supply
National Vitamin Company
Physicians Total Care Inc.
PruGen Inc. Pharmaceuticals
Rasi Laboratories Inc.
Seton Pharmaceuticals LLC
Ther-Rx Corp.
Synonyms1,2-Ethanedicarboxylic acid
Amber acid
Butanedioic acid
Butanedionic acid
Spirit of amber


For nutritional supplementation, also for treating dietary shortage or imbalance

mechanism of action

Succinate is an essential component of the Krebs or citric acid cycle and serves an electron donor in the production of fumaric acid and FADH2. It also has been shown to be a good "natural" antibiotic because of its relative acidic or caustic nature (high concentrations can even cause burns). Succinate supplements have been shown to help reduce the effects of hangovers by activating the degradation of acetaldehyde - a toxic byproduct of alcohol metabolism - into CO2 and H2O through aerobic metabolism. Succinic acid has been shown to stimulate neural system recovery and bolster the immune system. Claims have also been made that it boosts awareness, concentration and reflexes.


Oral rat LD50: 2260 mg/kg