indication

Used in combination with piperacillin to broaden the spectrum of piperacillin antibacterial action.

pharmacology

Tazobactam is a compound which inhibits the action of bacterial beta-lactamases. It is added to the extended spectrum beta-lactam antibiotic piperacillin.

mechanism of action

Tazobactam broadens the spectrum of piperacillin by making it effective against organisms that express beta-lactamase and would normally degrade piperacillin.

drug interactions

Demeclocycline: Possible antagonism of action

Doxycycline: Possible antagonism of action

Ethinyl Estradiol: This anti-infectious agent could decrease the effect of the oral contraceptive

Minocycline: Possible antagonism of action

Tetracycline: Possible antagonism of action