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A chemically stable, cytidine analog that displays anti-tumor properties. Acts as a transition state analog inhibitor of cytidine deaminase by binding to the active size as covalent hydrates. Also shown to inhibit DNA methylation and tumor growth both in vitro and in vivo. |
Synonyms | 1-beta-D-ribofuranosyl-2(1H)-pyrimidinone 1-beta-D-ribofuranosylpyrimidin-2(1H)-one DHZ Pyrimidin-2-one beta-D-ribofuranoside pyrimidin-2-one beta-ribofuranoside Pyrimidin-2-one ribonucleoside
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